Aburi Botanical Gardens is a botanical garden in Aburi in Eastern region of South Ghana.

The garden occupies an area of 64.8 hectares. It was opened in March, 1890. Before the garden was established, it was the site of a sanatorium built in 1875 for Gold Coast government officials. During the governorship of William Brandford-Griffith, a Basel missionary supervised clearing of land around the sanatorium to start the Botanic Department.

In 1890 William Crowther, a student from the Royal Botanic Gardens, Kew, was appointed the garden's first curator. The gardens played an important role in encouraging cocoa production in South Ghana, by supplying cheap cocoa seedlings and information about scientific farming methods. After Hevea Brasiliensis was sent to Aburi from Kew in 1893, the gardens also encouraged rubber production in Ghana.